If your dog is starting to slow down, seems like he’s in pain after exercise or struggles getting up steps, there’s a good chance what you’re seeing may be the effects of canine arthritis. Thankfully, when you recognize the signs early, you and your veterinarian can intervene in the progression of canine arthritis and may help your dog live a long, happy and energetic life.

  • The only FDA-approved, injectable, disease-modifying osteoarthritis drug (DMOAD) for dogs in the U.S.
  • Helps control the signs associated with non-infectious degenerative and/or traumatic arthritis of canine synovial joints.
  • Enters the joint quickly to control signs of canine arthritis.1

about canine arthritis

canine arthritis affects all kinds of dogs

While certain breeds are predisposed to canine arthritis — especially breeds with a history of hip and elbow dysplasia — canine arthritis is common among all kinds of dogs and is the most common cause of chronic pain.2 There are certain risk factors that can cause and aggravate canine arthritis, including traumatic injuries, genetic defects, obesity and age. While canine arthritis is often seen as a disease affecting older dogs, it does affect younger dogs as well.3

Canine arthritis is characterized by the degeneration of cartilage, which can cause painful bone-on-bone contact. Joints become inflamed and swell, causing dogs pain and discomfort, which can slow them down.

If you notice your dog slowing down, talk to your veterinarian right away. Treating your dog at the first signs of canine arthritis can make a big difference.

is your dog at risk?

recognizing the signs early can help your dog feel better sooner

Use the quiz below to see if your dog could be suffering from canine arthritis.Take these results to your veterinarian for a complete physical exam, diagnosis and discussion of appropriate treatment options.


Does your dog hesitate or show a reluctance to walk, run, play, climb stairs or jump in and out of the car?

Does your dog seem stiff or shaky when rising or walking?

Does your dog limp after strenuous play or exercise?

Has your dog had some kind of prior joint trauma?

Does your dog show signs of discomfort, such as whimpering or restlessness?

Does your dog have difficulty squatting to eliminate?

Yes No

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Because your dog is showing one or more of the signs of canine arthritis, print or email your dog’s results and talk with your veterinarian today.

After you purchase Adequan® Canine, use this code to redeem a rebate: 16-75624


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about adequan® canine

help your dog feel better and be more active

Adequan® Canine (polysulfated glycosaminoglycan) is the only FDA-approved, injectable, disease modifying osteoarthritis drug (DMOAD) for dogs in the U.S. that inhibits enzymes that break down cartilage, so joint damage is reduced. Treatment with Adequan® Canine travels to the joint quickly — within 2 hours — and it stays in the joint for up to three days.* Adequan® Canine is administered twice weekly for up to four weeks with a maximum of eight injections. You should see signs of improvement within a month.1

*Clinical significance unknown

canine joints commonly affected by arthritis

Irish setter with joints highlighted

a plan will help you fight canine arthritis

Together, you and your veterinarian can develop a plan that can help slow the progression of canine arthritis and may help your dog live an energetic, healthy life. Your dog's plan may include:

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other prescription drugs

Prescription medicine can help control the pain and inflammation associated with osteoarthritis.

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Extra pounds mean extra stress on joints, so managing weight is an important way to keep joints healthy.

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Even gentle activity helps keep joints limber and muscles strong, and aids in maintaining a healthy weight.

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physical therapy

Rehabilitation can improve joint health, strengthen muscles, aid healing and relieve pain.

Do you own horses?

Adequan® (polysulfated glycosaminoglycan) equine formulations are available at luitpoldanimalhealth.com.

Adequan® Canine is recommended for intramuscular injection for the control of signs associated with non-infectious degenerative and/or traumatic arthritis of canine synovial joints.

Important safety information

Adequan® Canine should not be used in dogs who are hypersensitive to PSGAG or who have a known or suspected bleeding disorder. It should be used with caution in dogs with renal or hepatic impairment. Adverse reactions in clinical studies (transient pain at injection site, transient diarrhea, and abnormal bleeding) were mild and self-limiting. In post approval experience, death has been reported in some cases; vomiting, anorexia, depression/lethargy and diarrhea have also been reported. The safe use of PSGAG in breeding, pregnant or lactating dogs has not been evaluated. For additional safety information, please see full prescribing information.